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Details
Link-It Detail - Disease - Cell Transformation, Neoplastic
Debug Stats
  • ### Total Build Time: 156 ms 44.177 KB
  • CONCEPT_NAME gt=2 ms Completed: 2 ms rowSize= 360 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 433 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 187 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 556 bytes
  • CONCEPT_CHILDREN gt=4 ms Completed: 4 ms rowSize= 994 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 2.793 KB
  • CONCEPT_RELATIONSHIPS gt=131 ms Completed: 131 ms rowSize= 14.850 KB
  • CONCEPT_GENES gt=17 ms Completed: 17 ms rowSize= 22.871 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.165 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Cell Transformation, Neoplastic C0007621
Definition (1)
Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.
Semantic Types (1)
Neoplastic Process (T191)
Parents (1)
img Neoplastic Processes C0027671
Children (2)
img Cell Transformation, Viral C0007622
img Blast Crisis C0005699
Ancestral Roots
RootRoot Plus OneDepthParent
img Neoplasms C0027651img Neoplastic Processes C00276713img Neoplastic Processes C0027671
img Pathological Conditions, Signs and Symptoms C0039058img Pathologic Processes C00306604img Neoplastic Processes C0027671
Relationships (480)

Relation Types:
diso_​to_​anat : 34
diso_​to_​chem : 127
diso_​to_​diso : 111
diso_​to_​gene : 173
diso_​to_​phen : 2
diso_​to_​phys : 33


Relationships:
none : 253
biological_​process_​is_​part_​of_​process : 5
gene_​plays_​role_​in_​process : 166
gene_​product_​plays_​role_​in_​biological_​process : 47
isa : 6
mapped_​to : 1
permuted_​term_​of : 1
use : 1
Page Size
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Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_PHEN1911img genetic aspects C0017399
DISO_to_PHEN1141img genetic aspects C0017399
DISO_to_DISO511img Neoplasms C0027651
DISO_to_DISO364img Neoplasms C0027651
DISO_to_PHYS278img GENE EXPRESSION REG NEOPL C0017268
DISO_to_PHYS248img Signal Transduction C0037083
DISO_to_DISO239img Breast Neoplasms C1458155
DISO_to_DISO226img chemically induced C0007994
DISO_to_PHYS205img GENE EXPRESSION REG NEOPL C0017268
DISO_to_DISO202img Cutaneous tumor C0037286
DISO_to_ANAT190img Epithelial Cells C0014597
DISO_to_DISO176img Precancerous Conditions C0032927
DISO_to_ANAT172img Cell, Neoplastic Stem C1956421
DISO_to_CHEM167img Binding Protein, DNA C0012940
DISO_to_DISO155img Carcinoma, Squamous Cell C0007137
DISO_to_PHYS153img Signal Transduction C0037083
DISO_to_DISO147img Breast Neoplasms C1458155
DISO_to_DISO146img Lung Neoplasms C0024121
DISO_to_DISO139img Cutaneous tumor C0037286
DISO_to_CHEM138img TRANSCRIPTION FACTOR C0040648
DISO_to_DISO136img Liver Neoplasms C0023903
DISO_to_DISO134img Adenocarcinoma C0001418
DISO_to_DISO127img COLORECTAL NEOPL C0009404
DISO_to_PHYS127img Apoptosis C0162638
DISO_to_PHYS125img Cell Proliferation C0596290
Genes (104)

Species:
human : 104
Page Size
Current 25
  Page 1 of 5
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Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanPACRG135138PARK2 co-regulated
INFERRED, Score=800, UMLKSK CUI: C0007621
HumanLHX489884LIM homeobox 4
INFERRED, Score=800, UMLKSK CUI: C0007621
HumanUBASH3B84959ubiquitin associated and SH3 domain containing B
INFERRED, Score=800, UMLKSK CUI: C0007621
HumanNUDCD184955NudC domain containing 1
INFERRED, Score=800, UMLKSK CUI: C0007621
HumanCDCA783879cell division cycle associated 7
INFERRED, Score=800, UMLKSK CUI: C0007621
HumanCDCP164866CUB domain containing protein 1
INFERRED, Score=800, UMLKSK CUI: C0007621
HumanBACH260468BTB and CNC homology 1, basic leucine zipper transcription factor 2
INFERRED, Score=800, UMLKSK CUI: C0007621
HumanPDCD427250programmed cell death 4 (neoplastic transformation inhibitor)
img GENERIF, Score=901, Pubmed Id: 17828298, UMLKSK CUI: C0007621
HumanNOX127035NADPH oxidase 1
img GENERIF, Score=1000, Pubmed Id: 18037128, UMLKSK CUI: C0007621
HumanGREM126585gremlin 1, DAN family BMP antagonist
img GENERIF, Score=1000, Pubmed Id: 12135612, UMLKSK CUI: C0007621
HumanSH2B125970SH2B adaptor protein 1
img GENERIF, Score=901, Pubmed Id: 17471236, UMLKSK CUI: C0007621
HumanEPB41L323136erythrocyte membrane protein band 4.1-like 3
img GENERIF, Score=1000, Pubmed Id: 16142420, UMLKSK CUI: C0007621
HumanAKAP1311214A kinase (PRKA) anchor protein 13
INFERRED, Score=800, UMLKSK CUI: C0007621
HumanTHOC19984THO complex 1
img GENERIF, Score=1000, Pubmed Id: 17638875, UMLKSK CUI: C0007621
HumanSOCS39021suppressor of cytokine signaling 3
INFERRED, Score=800, UMLKSK CUI: C0007621
HumanBCL108915B-cell CLL/lymphoma 10
INFERRED, Score=800, UMLKSK CUI: C0007621
HumanPROM18842prominin 1
INFERRED, Score=800, UMLKSK CUI: C0007621
HumanTP638626tumor protein p63
INFERRED, Score=800, UMLKSK CUI: C0007621
img GENERIF, Score=1000, Pubmed Id: 16273188, UMLKSK CUI: C0007621
HumanHMGA28091high mobility group AT-hook 2
INFERRED, Score=800, UMLKSK CUI: C0007621
HumanCXCR47852chemokine (C-X-C motif) receptor 4
INFERRED, Score=800, UMLKSK CUI: C0007621
HumanZNF2177764zinc finger protein 217
img GENERIF, Score=1000, Pubmed Id: 16203743, UMLKSK CUI: C0007621
HumanVPREB17441pre-B lymphocyte 1
INFERRED, Score=800, UMLKSK CUI: C0007621
HumanVDR7421vitamin D (1,25- dihydroxyvitamin D3) receptor
img GENERIF, Score=1000, Pubmed Id: 12957667, UMLKSK CUI: C0007621
HumanUNG7374uracil-DNA glycosylase
INFERRED, Score=800, UMLKSK CUI: C0007621
HumanTSPY17258testis specific protein, Y-linked 1
img GENERIF, Score=1000, Pubmed Id: 15948118, UMLKSK CUI: C0007621
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0007621Cell Transformation, Neoplastic0self