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Details
Link-It Detail - Disease - Carotid Artery Diseases
Debug Stats
  • ### Total Build Time: 88 ms 42.391 KB
  • CONCEPT_NAME gt=10 ms Completed: 10 ms rowSize= 394 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
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  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
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  • CONCEPT_CHILDREN gt=3 ms Completed: 3 ms rowSize= 2.712 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 2.805 KB
  • CONCEPT_RELATIONSHIPS gt=54 ms Completed: 54 ms rowSize= 13.950 KB
  • CONCEPT_GENES gt=15 ms Completed: 15 ms rowSize= 19.427 KB
  • CONCEPT_XREFS gt=0 Completed: 0 ms rowSize= 1.157 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (2)
Carotid Artery Diseases C0007273
ARTERIAL DIS CAROTID
Definition (1)

Your carotid arteries are two large blood vessels in your neck. They supply your brain with blood. If you have carotid artery disease, the arteries become narrow, usually because of atherosclerosis. This is the buildup of cholesterol and other material in an artery. If a blood clot sticks in the narrowed arteries, blood can't reach your brain. This is one of the causes of stroke.

Carotid artery disease often does not cause symptoms, but there are tests that can tell your doctor if you have it. If the arteries are very narrow, you may need an operation called an endarterectomy to remove the plaque. For less severe narrowing, a medicine to prevent blood clots can reduce your risk of stroke. Another option for people who can't have surgery is carotid angioplasty. This involves placing balloons and/or stents into the artery to open it and hold it open.

Semantic Types (1)
Disease or Syndrome (T047)
Parents (1)
img Cerebrovascular Disorders C0007820
Children (6)
img Carotid Artery, Internal, Dissection C0751815
img Carotid Artery Thrombosis C0007274
img Carotid Stenosis C0007282
img Moyamoya Disease C0026654
img Carotid-Cavernous Sinus Fistula C0238045
img Carotid Artery Injuries C0160680
Ancestral Roots
RootRoot Plus OneDepthParent
img Nervous System Diseases C0027765img Central Nervous System Diseases C00076825img Cerebrovascular Disorders C0007820
img Cardiovascular Diseases C0007222img Vascular Diseases C00423734img Cerebrovascular Disorders C0007820
Relationships (168)

Relation Types:
diso_​to_​anat : 28
diso_​to_​chem : 17
diso_​to_​diso : 105
diso_​to_​gene : 1
diso_​to_​phen : 3
diso_​to_​phys : 14


Relationships:
none : 146
is_​associated_​anatomic_​site_​of : 2
isa : 16
permuted_​term_​of : 1
related_​to : 3
Page Size
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Prior Page
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Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO564img Complication Aspects C1171258
DISO_to_ANAT412img Carotid Arteries C0007272
DISO_to_DISO349img Complication Aspects C1171258
DISO_to_ANAT292img In Blood C0005768
DISO_to_ANAT277img Carotid Artery, Internal C0007276
DISO_to_DISO247img Atherosclerosis C0004153
DISO_to_ANAT229img Carotid Artery, Common C0162859
DISO_to_ANAT214img Tunica Intima C0162864
DISO_to_ANAT210img Carotid Artery, Internal C0007276
DISO_to_DISO180img Cerebrovascular accident C0038454
DISO_to_ANAT176img In Blood C0005768
DISO_to_PHEN175img genetic aspects C0017399
DISO_to_ANAT173img Carotid Arteries C0007272
DISO_to_ANAT162img Tunica Media C0162867
DISO_to_ANAT147img Carotid Artery, Common C0162859
DISO_to_DISO141img ANEURYSM INTRACRANIAL C0007766
DISO_to_DISO132img Arteriosclerosis C0003850
DISO_to_DISO127img ANEURYSM INTRACRANIAL C0007766
DISO_to_DISO125img Coronary Artery Disease C1956346
DISO_to_DISO107img Aneurysm C0002940
DISO_to_DISO105img Diabetes Mellitus, Non-Insulin-Dependent C0011860
DISO_to_DISO101img Aneurysm C0002940
DISO_to_ANAT100img Tunica Intima C0162864
DISO_to_DISO91img Cerebrovascular accident C0038454
DISO_to_PHEN90img genetic aspects C0017399
Genes (27)

Species:
human : 27
Page Size
Current 25
  Page 1 of 2
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanSMARCAL150485SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
INFERRED, Score=800, UMLKSK CUI: C0007273
HumanSLC39A229986solute carrier family 39 (zinc transporter), member 2
img GENERIF, Score=1000, Pubmed Id: 18328005, UMLKSK CUI: C0007273
HumanSGCE8910sarcoglycan, epsilon
INFERRED, Score=800, UMLKSK CUI: C0007273
HumanVCAM17412vascular cell adhesion molecule 1
INFERRED, Score=800, UMLKSK CUI: C0007273
HumanTTR7276transthyretin
INFERRED, Score=800, UMLKSK CUI: C0007273
HumanTIMP27077TIMP metallopeptidase inhibitor 2
INFERRED, Score=800, UMLKSK CUI: C0007273
HumanTIMP17076TIMP metallopeptidase inhibitor 1
INFERRED, Score=800, UMLKSK CUI: C0007273
HumanSPP16696secreted phosphoprotein 1
INFERRED, Score=800, UMLKSK CUI: C0007273
HumanPON15444paraoxonase 1
img GENERIF, Score=1000, Pubmed Id: 12805074, UMLKSK CUI: C0007273
img GENERIF, Score=884, Pubmed Id: 16474172, UMLKSK CUI: C0007273
HumanNOS34846nitric oxide synthase 3 (endothelial cell)
INFERRED, Score=800, UMLKSK CUI: C0007273
HumanMTHFR4524methylenetetrahydrofolate reductase (NAD(P)H)
INFERRED, Score=800, UMLKSK CUI: C0007273
HumanMT2A4502metallothionein 2A
INFERRED, Score=800, UMLKSK CUI: C0007273
HumanMMP94318matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
INFERRED, Score=800, UMLKSK CUI: C0007273
HumanMMP34314matrix metallopeptidase 3 (stromelysin 1, progelatinase)
INFERRED, Score=800, UMLKSK CUI: C0007273
HumanMMP24313matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
INFERRED, Score=800, UMLKSK CUI: C0007273
HumanMMP14312matrix metallopeptidase 1 (interstitial collagenase)
INFERRED, Score=800, UMLKSK CUI: C0007273
HumanLPA4018lipoprotein, Lp(a)
INFERRED, Score=800, UMLKSK CUI: C0007273
HumanLIPC3990lipase, hepatic
INFERRED, Score=800, UMLKSK CUI: C0007273
HumanIL63569interleukin 6 (interferon, beta 2)
img GENERIF, Score=923, Pubmed Id: 17115186, UMLKSK CUI: C0007273
HumanHIF1A3091hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
INFERRED, Score=800, UMLKSK CUI: C0007273
HumanHGF3082hepatocyte growth factor (hepapoietin A; scatter factor)
INFERRED, Score=800, UMLKSK CUI: C0007273
HumanF22147coagulation factor II (thrombin)
INFERRED, Score=800, UMLKSK CUI: C0007273
HumanENG2022endoglin
INFERRED, Score=800, UMLKSK CUI: C0007273
HumanCRP1401C-reactive protein, pentraxin-related
INFERRED, Score=800, UMLKSK CUI: C0007273
HumanCRABP11381cellular retinoic acid binding protein 1
INFERRED, Score=800, UMLKSK CUI: C0007273
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0007273Carotid Artery Diseases0self