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Details
Link-It Detail - Disease - Blast Crisis
Debug Stats
  • ### Total Build Time: 101 ms 65.101 KB
  • CONCEPT_NAME gt=4 ms Completed: 4 ms rowSize= 322 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 400 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=2 ms Completed: 2 ms rowSize= 1.009 KB
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=5 ms Completed: 5 ms rowSize= 5.422 KB
  • CONCEPT_RELATIONSHIPS gt=54 ms Completed: 54 ms rowSize= 16.354 KB
  • CONCEPT_GENES gt=34 ms Completed: 34 ms rowSize= 40.246 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.146 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Blast Crisis C0005699
Definition (1)
A phase of chronic myelogenous leukemia in which 20% or more of the cells in the blood or bone marrow are blast cells (immature blood cells). When tiredness, fever, and an enlarged spleen occur during the blastic phase, it is called blast crisis.
Semantic Types (1)
Disease or Syndrome (T047)
Parents (2)
img Cell Transformation, Neoplastic C0007621
img Leukemia, Myelogenous, Chronic, BCR-ABL Positive C0023473
Ancestral Roots
RootRoot Plus OneDepthParent
img Neoplasms C0027651img Neoplastic Processes C00276714img Cell Transformation, Neoplastic C0007621
img Pathological Conditions, Signs and Symptoms C0039058img Pathologic Processes C00306605img Cell Transformation, Neoplastic C0007621
img Neoplasms C0027651img Neoplasms by Histologic Type C00276526img Leukemia, Myelogenous, Chronic, BCR-ABL Positive C0023473
img Hemic and Lymphatic Diseases C0018981img Hematologic Diseases C00189396img Leukemia, Myelogenous, Chronic, BCR-ABL Positive C0023473
Relationships (79)

Relation Types:
diso_​to_​anat : 16
diso_​to_​chem : 16
diso_​to_​diso : 40
diso_​to_​phen : 4
diso_​to_​phys : 3


Relationships:
none : 30
clinically_​similar : 1
is_​abnormal_​cell_​of_​disease : 6
is_​finding_​of_​disease : 2
is_​normal_​cell_​origin_​of_​disease : 3
is_​normal_​tissue_​origin_​of_​disease : 2
is_​not_​finding_​of_​disease : 2
is_​not_​molecular_​abnormality_​of_​disease : 3
is_​not_​normal_​cell_​origin_​of_​disease : 1
is_​primary_​anatomic_​site_​of_​disease : 2
isa : 2
may_​be_​associated_​disease_​of_​disease : 1
may_​be_​cytogenetic_​abnormality_​of_​disease : 8
may_​be_​finding_​of_​disease : 6
may_​be_​molecular_​abnormality_​of_​disease : 4
may_​treat : 5
permuted_​term_​of : 1
Page Size
Current 25
  Page 1 of 4
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO125img Leukemia, Myelogenous, Chronic, BCR-ABL Positive C0023473
DISO_to_DISO118img Leukemia, Myelogenous, Chronic, BCR-ABL Positive C0023473
DISO_to_PHEN83img genetic aspects C0017399
DISO_to_PHEN53img genetic aspects C0017399
DISO_to_CHEM47img Piperazines C0031958
DISO_to_CHEM47img Pyrimidines C0034289
DISO_to_CHEM43img Pyrimidines C0034289
DISO_to_DISO39img Leukemia, Myelocytic, Acute C0023467
DISO_to_CHEM36img Piperazines C0031958
DISO_to_CHEM34img Antineoplastic Agents C0003392
DISO_to_CHEM27img Antineoplastic Agents C0003392
DISO_to_CHEM23img Fusion Proteins, bcr-abl C0004891
DISO_to_DISO18img Precursor Cell Lymphoblastic Leukemia Lymphoma C1961102
DISO_to_CHEM17img Protein Kinase Inhibitors C1449702
DISO_to_PHYS16img Mutation C0026882
DISO_to_CHEM15img Fusion Proteins, bcr-abl C0004891
DISO_to_DISO15img Leukemia, Myeloid C0023470
DISO_to_PHYS14img GENE EXPRESSION REG LEUKEMIC C0017267
DISO_to_ANAT11img In Blood C0005768
DISO_to_DISO11img Complication Aspects C1171258
DISO_to_DISO11img Precursor Cell Lymphoblastic Leukemia Lymphoma C1961102
DISO_to_PHYS11img Drug Resistance, Neoplasm C0282588
DISO_to_ANAT10img In Blood C0005768
DISO_to_DISO10img Complication Aspects C1171258
DISO_to_DISO10img Dysmyelopoietic Syndromes C0026986
Genes (70)

Species:
human : 67
mouse : 3
Page Size
Current 25
  Page 1 of 3
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
MouseNUP984928nucleoporin 98kDa
img NCI, Score=801, Pubmed Id: 12032333, UMLKSK CUI: C0005699
img NCI, Score=801, Pubmed Id: 12032333, UMLKSK CUI: C0005699
MouseJUNB3726jun B proto-oncogene
img NCI, Score=801, Pubmed Id: 11163237, UMLKSK CUI: C0005699
img NCI, Score=801, Pubmed Id: 12506033, UMLKSK CUI: C0005699
MouseHOXA93205homeobox A9
img NCI, Score=801, Pubmed Id: 12032333, UMLKSK CUI: C0005699
img NCI, Score=801, Pubmed Id: 12032333, UMLKSK CUI: C0005699
HumanPACRG135138PARK2 co-regulated
img NCI, Score=801, Pubmed Id: 16287063, UMLKSK CUI: C0005699
HumanLHX489884LIM homeobox 4
img NCI, Score=801, Pubmed Id: 14506703, UMLKSK CUI: C0005699
HumanUBASH3B84959ubiquitin associated and SH3 domain containing B
img GENERIF, Score=840, Pubmed Id: 15388581, UMLKSK CUI: C0005699
HumanNUDCD184955NudC domain containing 1
img NCI, Score=801, Pubmed Id: 15958636, UMLKSK CUI: C0005699
img NCI, Score=801, Pubmed Id: 15958636, UMLKSK CUI: C0005699
img NCI, Score=801, Pubmed Id: 15958636, UMLKSK CUI: C0005699
HumanCDCA783879cell division cycle associated 7
img NCI, Score=801, Pubmed Id: 15994934, UMLKSK CUI: C0005699
HumanCDCP164866CUB domain containing protein 1
img NCI, Score=801, Pubmed Id: 15153610, UMLKSK CUI: C0005699
HumanBACH260468BTB and CNC homology 1, basic leucine zipper transcription factor 2
img NCI, Score=801, Pubmed Id: 11746976, UMLKSK CUI: C0005699
HumanAKAP1311214A kinase (PRKA) anchor protein 13
img NCI, Score=801, Pubmed Id: 367348, UMLKSK CUI: C0005699
img NCI, Score=801, Pubmed Id: 2049463, UMLKSK CUI: C0005699
img NCI, Score=801, Pubmed Id: 10559334, UMLKSK CUI: C0005699
img NCI, Score=801, Pubmed Id: 11696353, UMLKSK CUI: C0005699
HumanSOCS39021suppressor of cytokine signaling 3
img NCI, Score=801, Pubmed Id: 12351404, UMLKSK CUI: C0005699
img NCI, Score=801, Pubmed Id: 12351404, UMLKSK CUI: C0005699
HumanBCL108915B-cell CLL/lymphoma 10
img NCI, Score=801, Pubmed Id: 10557068, UMLKSK CUI: C0005699
img GAD, Score=1000, Pubmed Id: 10557068, UMLKSK CUI: C0005699
HumanPROM18842prominin 1
img NCI, Score=801, Pubmed Id: 11224484, UMLKSK CUI: C0005699
HumanTP638626tumor protein p63
img GAD, Score=964, Pubmed Id: 11681414, UMLKSK CUI: C0005699
HumanHMGA28091high mobility group AT-hook 2
img GENERIF, Score=840, Pubmed Id: 17917968, UMLKSK CUI: C0005699
HumanCXCR47852chemokine (C-X-C motif) receptor 4
img NCI, Score=801, Pubmed Id: 15805265, UMLKSK CUI: C0005699
HumanVPREB17441pre-B lymphocyte 1
img NCI, Score=801, Pubmed Id: 1884024, UMLKSK CUI: C0005699
HumanUNG7374uracil-DNA glycosylase
img NCI, Score=801, Pubmed Id: 3474482, UMLKSK CUI: C0005699
img NCI, Score=801, Pubmed Id: 3474482, UMLKSK CUI: C0005699
HumanTGFB27042transforming growth factor, beta 2
img NCI, Score=801, Pubmed Id: 10559334, UMLKSK CUI: C0005699
HumanTAL16886T-cell acute lymphocytic leukemia 1
img NCI, Score=801, Pubmed Id: 7579412, UMLKSK CUI: C0005699
HumanSTAT5B6777signal transducer and activator of transcription 5B
img NCI, Score=801, Pubmed Id: 15089759, UMLKSK CUI: C0005699
HumanSTAT5A6776signal transducer and activator of transcription 5A
img NCI, Score=801, Pubmed Id: 15089759, UMLKSK CUI: C0005699
HumanSET6418SET nuclear oncogene
img GENERIF, Score=901, Pubmed Id: 16286244, UMLKSK CUI: C0005699
HumanRGS25997regulator of G-protein signaling 2, 24kDa
img NCI, Score=801, Pubmed Id: 7643615, UMLKSK CUI: C0005699
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0005699Blast Crisis0self