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Details
Link-It Detail - Disease - Barrett Esophagus
Debug Stats
  • ### Total Build Time: 57 ms 58.787 KB
  • CONCEPT_NAME gt=14 ms Completed: 14 ms rowSize= 332 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 561 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=3 ms Completed: 3 ms rowSize= 1,003 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 4.145 KB
  • CONCEPT_RELATIONSHIPS gt=26 ms Completed: 26 ms rowSize= 15.923 KB
  • CONCEPT_GENES gt=12 ms Completed: 12 ms rowSize= 35.498 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.151 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Barrett Esophagus C0004763
Definition (1)
A condition with damage to the lining of the lower ESOPHAGUS resulting from chronic acid reflux (ESOPHAGITIS, REFLUX). Through the process of metaplasia, the squamous cells are replaced by a columnar epithelium with cells resembling those of the INTESTINE or the salmon-pink mucosa of the STOMACH. Barrett's columnar epithelium is a marker for severe reflux and precursor to ADENOCARCINOMA of the esophagus.
Semantic Types (1)
Disease or Syndrome (T047)
Parents (2)
img Esophageal Diseases C0014852
img Digestive System Abnormalities C0266015
Ancestral Roots
RootRoot Plus OneDepthParent
img Digestive System Diseases C0012242img Gastrointestinal Diseases C00171784img Esophageal Diseases C0014852
img Congenital, Hereditary, and Neonatal Diseases and Abnormalities C0027612img Congenital Abnormalities C00007684img Digestive System Abnormalities C0266015
img Digestive System Diseases C0012242img Digestive System Abnormalities C02660153img Digestive System Abnormalities C0266015
Relationships (88)

Relation Types:
diso_​to_​anat : 20
diso_​to_​chem : 19
diso_​to_​diso : 43
diso_​to_​gene : 2
diso_​to_​phen : 2
diso_​to_​phys : 2


Relationships:
none : 62
associated_​with : 1
classifies : 2
disease_​has_​associated_​disease : 2
gene_​associated_​with_​disease : 2
gene_​product_​malfunction_​associated_​with_​disease : 1
is_​associated_​anatomic_​site_​of : 2
is_​finding_​of_​disease : 1
isa : 1
location_​of : 5
manifestation_​of : 1
mapped_​to : 2
may_​be_​associated_​disease_​of_​disease : 1
may_​be_​finding_​of_​disease : 1
may_​be_​molecular_​abnormality_​of_​disease : 3
related_​to : 1
Page Size
Current 25
  Page 1 of 4
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO732img Esophageal Neoplasms C0014859
DISO_to_DISO570img Esophageal Neoplasms C0014859
DISO_to_DISO551img Adenocarcinoma C0001418
DISO_to_DISO425img Adenocarcinoma C0001418
DISO_to_DISO316img Precancerous Conditions C0032927
DISO_to_DISO251img Complication Aspects C1171258
DISO_to_DISO246img Complication Aspects C1171258
DISO_to_ANAT220img Esophagus C0014876
DISO_to_DISO208img Precancerous Conditions C0032927
DISO_to_PHEN208img genetic aspects C0017399
DISO_to_DISO173img Gastroesophageal Reflux C0017168
DISO_to_DISO168img Gastroesophageal Reflux C0017168
DISO_to_PHEN149img genetic aspects C0017399
DISO_to_ANAT144img Esophagus C0014876
DISO_to_CHEM54img BIOCHEM TUMOR MARKERS C0041366
DISO_to_DISO42img Esophagitis C0014868
DISO_to_ANAT39img Esophagogastric Junction C0014871
DISO_to_DISO34img Esophagitis, Peptic C0014869
DISO_to_CHEM32img Proton Pump Inhibitors C0358591
DISO_to_DISO31img Carcinoma, Squamous Cell C0007137
DISO_to_ANAT29img Intestinal Mucosa C0021839
DISO_to_ANAT28img Esophagogastric Junction C0014871
DISO_to_CHEM27img Proton Pump C0018440
DISO_to_ANAT26img Cardia C0007144
DISO_to_CHEM26img Homeo Domain Proteins C0242617
Genes (21)

Species:
human : 21
SpeciesGeneGeneIdGene NameEvidence
HumanANXA1011199annexin A10
img NCI, Score=801, Pubmed Id: 16230080, UMLKSK CUI: C0004763
HumanPTGES9536prostaglandin E synthase
img NCI, Score=801, Pubmed Id: 16143029, UMLKSK CUI: C0004763
img NCI, Score=801, Pubmed Id: 16143029, UMLKSK CUI: C0004763
HumanCES28824carboxylesterase 2
img NCI, Score=801, Pubmed Id: 15967118, UMLKSK CUI: C0004763
HumanTFF27032trefoil factor 2
img NCI, Score=801, Pubmed Id: 12152167, UMLKSK CUI: C0004763
img NCI, Score=801, Pubmed Id: 12152167, UMLKSK CUI: C0004763
img NCI, Score=801, Pubmed Id: 12152167, UMLKSK CUI: C0004763
HumanTFF17031trefoil factor 1
img NCI, Score=801, Pubmed Id: 12152167, UMLKSK CUI: C0004763
HumanSOD26648superoxide dismutase 2, mitochondrial
img NCI, Score=801, Pubmed Id: 15884106, UMLKSK CUI: C0004763
HumanPITX15307paired-like homeodomain 1
img NCI, Score=801, Pubmed Id: 16291394, UMLKSK CUI: C0004763
img NCI, Score=801, Pubmed Id: 16291394, UMLKSK CUI: C0004763
img NCI, Score=801, Pubmed Id: 16291394, UMLKSK CUI: C0004763
img NCI, Score=801, Pubmed Id: 16291394, UMLKSK CUI: C0004763
HumanPGC5225progastricsin (pepsinogen C)
img NCI, Score=801, Pubmed Id: 11471898, UMLKSK CUI: C0004763
img NCI, Score=801, Pubmed Id: 3305135, UMLKSK CUI: C0004763
HumanMUC5AC4586mucin 5AC, oligomeric mucus/gel-forming
img NCI, Score=801, Pubmed Id: 14535999, UMLKSK CUI: C0004763
img NCI, Score=801, Pubmed Id: 14631367, UMLKSK CUI: C0004763
img NCI, Score=801, Pubmed Id: 16143029, UMLKSK CUI: C0004763
img NCI, Score=801, Pubmed Id: 12152167, UMLKSK CUI: C0004763
HumanMTAP4507methylthioadenosine phosphorylase
img NCI, Score=801, Pubmed Id: 16224217, UMLKSK CUI: C0004763
HumanMCM24171minichromosome maintenance complex component 2
img NCI, Score=801, Pubmed Id: 12855631, UMLKSK CUI: C0004763
HumanLTA4H4048leukotriene A4 hydrolase
img NCI, Score=801, Pubmed Id: 12865451, UMLKSK CUI: C0004763
HumanKRT133860keratin 13
img NCI, Score=801, Pubmed Id: 11521979, UMLKSK CUI: C0004763
HumanGRB72886growth factor receptor-bound protein 7
img NCI, Score=801, Pubmed Id: 15386389, UMLKSK CUI: C0004763
HumanGPX22877glutathione peroxidase 2 (gastrointestinal)
img NCI, Score=801, Pubmed Id: 12704661, UMLKSK CUI: C0004763
HumanFRZB2487frizzled-related protein
img NCI, Score=801, Pubmed Id: 15825175, UMLKSK CUI: C0004763
img NCI, Score=801, Pubmed Id: 15825175, UMLKSK CUI: C0004763
HumanFGF12246fibroblast growth factor 1 (acidic)
img NCI, Score=801, Pubmed Id: 11422301, UMLKSK CUI: C0004763
img NCI, Score=801, Pubmed Id: 11422301, UMLKSK CUI: C0004763
HumanEZH22146enhancer of zeste homolog 2 (Drosophila)
img NCI, Score=801, Pubmed Id: 16447267, UMLKSK CUI: C0004763
img NCI, Score=801, Pubmed Id: 16447267, UMLKSK CUI: C0004763
HumanEYA42070eyes absent homolog 4 (Drosophila)
img NCI, Score=801, Pubmed Id: 15824152, UMLKSK CUI: C0004763
img NCI, Score=801, Pubmed Id: 15824152, UMLKSK CUI: C0004763
img NCI, Score=801, Pubmed Id: 15824152, UMLKSK CUI: C0004763
HumanENG2022endoglin
img NCI, Score=801, Pubmed Id: 16153457, UMLKSK CUI: C0004763
HumanFRA3B0
img NCI, Score=801, Pubmed Id: 9349498, UMLKSK CUI: C0004763
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0004763Barrett Esophagus0self