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Details
Link-It Detail - Disease - Aphasia, Broca
Debug Stats
  • ### Total Build Time: 19 ms 15.924 KB
  • CONCEPT_NAME gt=3 ms Completed: 3 ms rowSize= 369 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
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  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
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  • CONCEPT_GENES gt=3 ms Completed: 3 ms rowSize= 1.332 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.148 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (2)
Aphasia, Broca C0003550
APHASIA MOTOR
Definition (1)
An aphasia characterized by impairment of expressive language (speech, writing, signs) and relative preservation of receptive language abilities (i.e., comprehension). This condition is caused by lesions of the motor association cortex in the frontal lobe (Broca's area and adjacent cortical and white matter regions). The deficits range from almost complete muteness to a reduction in the fluency and rate of speech. CEREBROVASCULAR ACCIDENTS (in particular INFARCTION, MIDDLE CEREBRAL ARTERY) are a relatively common cause of this condition. (From Adams et al., Principles of Neurology, 6th ed, pp478-9)
Semantic Types (1)
Mental or Behavioral Dysfunction (T048)
Parents (1)
img Aphasia C0003537
Ancestral Roots
RootRoot Plus OneDepthParent
img Mental Disorders C0004936img Mental Disorders Diagnosed in Childhood C05250407img Aphasia C0003537
img Pathological Conditions, Signs and Symptoms C0039058img Signs and Symptoms C00370889img Aphasia C0003537
img Nervous System Diseases C0027765img Neurologic Manifestations C00278548img Aphasia C0003537
img Behavior and Behavior Mechanisms C0004928img Neurobehavioral Manifestations C05250417img Aphasia C0003537
Relationships (14)

Relation Types:
diso_​to_​anat : 3
diso_​to_​diso : 7
diso_​to_​phys : 4


Relationships:
none : 12
isa : 1
permuted_​term_​of : 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO23img Aphasia, Wernicke C1510456
DISO_to_DISO21img Aphasia, Wernicke C1510456
DISO_to_ANAT20img Frontal Lobe C0016733
DISO_to_ANAT19img Frontal Lobe C0016733
DISO_to_DISO19img Cerebrovascular accident C0038454
DISO_to_PHYS18img Speech C0037817
DISO_to_DISO14img Anomia C0003113
DISO_to_PHYS11img Perception, Speech C0037826
DISO_to_ANAT10img Brain C0006104
DISO_to_DISO10img Cerebral Infarction C0007785
DISO_to_PHYS10img Perception, Speech C0037826
DISO_to_PHYS9img Comprehension C0162340
DISO_to_DISOpermuted_term_ofimg APHASIA MOTOR C0003550
DISO_to_DISOisaimg O/E - motor aphasia C0437226
Genes (1)

Species:
human : 1
SpeciesGeneGeneIdGene NameEvidence
HumanGJB12705gap junction protein, beta 1, 32kDa
img OMIM, Score=1000, UMLKSK CUI: C0003550
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0003550Aphasia, Broca0self