Human | SLC2A10 | 81031 | solute carrier family 2 (facilitated glucose transporter), member 10 | INFERRED, Score=800, UMLKSK CUI: C0002940 |
Human | SOX17 | 64321 | SRY (sex determining region Y)-box 17 | INFERRED, Score=800, UMLKSK CUI: C0002940 |
Human | XYLT1 | 64131 | xylosyltransferase I | INFERRED, Score=800, UMLKSK CUI: C0002940 |
Human | RTN4 | 57142 | reticulon 4 | Reduction of Nogo-B protein expression in thoracic aortic aneurysms is closely correlated to the formation of aneurysm and that Nogo-B may play a protective role in the pathological process of aneurysms |
Human | RETN | 56729 | resistin | INFERRED, Score=800, UMLKSK CUI: C0002940 |
Human | EFEMP2 | 30008 | EGF containing fibulin-like extracellular matrix protein 2 | INFERRED, Score=800, UMLKSK CUI: C0002940 |
Human | HPSE | 10855 | heparanase | INFERRED, Score=800, UMLKSK CUI: C0002940 |
Human | FBLN5 | 10516 | fibulin 5 | INFERRED, Score=800, UMLKSK CUI: C0002940 |
Human | ADIPOQ | 9370 | adiponectin, C1Q and collagen domain containing | INFERRED, Score=800, UMLKSK CUI: C0002940 |
Human | PLA2G7 | 7941 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) | Title:Association of a G994 -->T missense mutation in the plasma platelet-activating factor acetylhydrolase gene with risk of abdominal aortic aneurysm in Japanese.|Association:Y|Conclusion:The genetic mutation of plasma PAF-AH gene appear to be an independent risk factor for AAA. Our findings need to be confirmed in a larger, prospective study including patients from different populations. |
Human | TNF | 7124 | tumor necrosis factor | Higher cytosol levels of TNFA were found in the walls of ruptured aneurysms than in the asymptomatic aneurysms |
Human | TIMP3 | 7078 | TIMP metallopeptidase inhibitor 3 | INFERRED, Score=800, UMLKSK CUI: C0002940 |
Human | TIMP2 | 7077 | TIMP metallopeptidase inhibitor 2 | INFERRED, Score=800, UMLKSK CUI: C0002940 |
Human | TIMP1 | 7076 | TIMP metallopeptidase inhibitor 1 | hTIMP-1 reduces aneurysm formation in ApoE(-/-) mice but does not protect them against the development of arterial lesions |
Human | TGFBR2 | 7048 | transforming growth factor, beta receptor II (70/80kDa) | INFERRED, Score=800, UMLKSK CUI: C0002940 |
Human | TGFBR1 | 7046 | transforming growth factor, beta receptor 1 | INFERRED, Score=800, UMLKSK CUI: C0002940 |
Human | TGFB1 | 7040 | transforming growth factor, beta 1 | INFERRED, Score=800, UMLKSK CUI: C0002940 |
Human | CX3CL1 | 6376 | chemokine (C-X3-C motif) ligand 1 | INFERRED, Score=800, UMLKSK CUI: C0002940 |
Human | PROC | 5624 | protein C (inactivator of coagulation factors Va and VIIIa) | Patients with abdominal aortic aneurysm have increased thrombin generation reflected by an increase in the activated protein C-protein C inhibitor complex, which correlates with aneurysm size |
Human | PRKCB | 5579 | protein kinase C, beta | INFERRED, Score=800, UMLKSK CUI: C0002940 |
Human | PRF1 | 5551 | perforin 1 (pore forming protein) | INFERRED, Score=800, UMLKSK CUI: C0002940 |
Human | PKD1 | 5310 | polycystic kidney disease 1 (autosomal dominant) | INFERRED, Score=800, UMLKSK CUI: C0002940 |
Human | SERPINA1 | 5265 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | INFERRED, Score=800, UMLKSK CUI: C0002940 |
Human | SERPINE1 | 5054 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | Title:The influence of 4G/5G polymorphism in the plasminogen activator inhibitor-1 gene promoter on the incidence, growth and operative risk of abdominal aortic aneurysm.|Association:Y|Conclusion:polymorphism of the PAI-1 gene promoter does not influence the development of AAA, although AAA growth is faster for patients of 5G5G genotype. However, this genotype (5G5G), which is associated with enhanced fibrinolysis, appears protective following open aneurysm repair. This effect of PAI-1 genotype on survival following surgery is likely to have widespread significance in vascular and general surgery. |
Human | NOTCH1 | 4851 | notch 1 | INFERRED, Score=800, UMLKSK CUI: C0002940 |