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Genes (39)
Species: human : 39 | |
Human | IL28RA | 163702 | | Results suggested that the g.32349 G>A polymorphism of IL-28RA might be associated with susceptibility to allergic rhinitis | Human | ATOD5 | 117188 | Dermatitis, atopic, 5 | | Human | ATOD3 | 117187 | Dermatitis, atopic, 3 | | Human | ATOD6 | 114477 | Dermatitis, atopic, 6 | | Human | ADAM33 | 80332 | ADAM metallopeptidase domain 33 | Title:Polymorphisms in ADAM33 are associated with allergic rhinitis due to Japanese cedar pollen|Association:Y|Conclusion:These results indicate that polymorphisms in the ADAM33 gene are associated with susceptibility to allergic rhinitis due to Japanese cedar pollen, but the functional relationship still needs clarification. | Human | ADIPOQ | 9370 | adiponectin, C1Q and collagen domain containing | This preliminary study provides the first evidence of significantly higher adiponectin serum levels in male patients with pollen-induced allergic rhinitis as compared to normal male subjects | Human | SCGB1A1 | 7356 | secretoglobin, family 1A, member 1 (uteroglobin) | Reduction in anti-inflammatory activity by CC16 may contribute to the pathogenesis of allergic rhinitis | Human | UCN | 7349 | urocortin | In allergic nasal mucosa, increased expression levels of urocortin and its receptors may contribute to increased mucosal swelling and vascular permeability, playing an important role in the pathogenesis of allergic rhinitis | Human | TNF | 7124 | tumor necrosis factor | Title:Association between TNF-alpha and TGF-beta genotypes in infants and parental history of allergic rhinitis and asthma.|Association:Y|Conclusion:These results suggest a role for TNF-alpha and TGF-beta1 genotypes in the pathogenesis of allergic rhinitis and asthma, respectively. If confirmed by future studies, cytokine genotyping may be a useful tool for identifying at-risk infants who may benefit from the selective use of preventative and/or early intervention treatments for these disorders. | Human | TLR4 | 7099 | toll-like receptor 4 | The up-regulation of Toll-like receptors 2, 3 and 4 in the nasal mucosa of patients with symptomatic allergic rhinitis supports the idea of a role for Toll-like receptors in allergic airway inflammation | Human | TGFB1 | 7040 | transforming growth factor, beta 1 | Title:Association between TNF-alpha and TGF-beta genotypes in infants and parental history of allergic rhinitis and asthma.|Association:Y|Conclusion:These results suggest a role for TNF-alpha and TGF-beta1 genotypes in the pathogenesis of allergic rhinitis and asthma, respectively. If confirmed by future studies, cytokine genotyping may be a useful tool for identifying at-risk infants who may benefit from the selective use of preventative and/or early intervention treatments for these disorders. | Human | TAP2 | 6891 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) | TAP1 but not TAP2 gene polymorphism may be an important factor contributing to the genetic susceptibility in the development of allergic rhinitis in the Korean population | Human | TAP1 | 6890 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | TAP1 but not TAP2 gene polymorphism may be an important factor contributing to the genetic susceptibility in the development of allergic rhinitis in the Korean population | Human | CX3CL1 | 6376 | chemokine (C-X3-C motif) ligand 1 | increased circulating levels in symptomatic allergic rhinitis and asthmatic patients | Human | CCL5 | 6352 | chemokine (C-C motif) ligand 5 | Title:Chemokine RANTES promoter polymorphisms in allergic rhinitis.|Association:Not Found|Conclusion:The study results indicated that the -403 and -28 alleles in the RANTES promoter region belong to the predictor gene set for allergic rhinitis and could be used in genomic analysis. The study results indicated that the -403 and -28 alleles in the RANTES promoter region belong to the predictor gene set for allergic rhinitis and could be used in genomic analysis | Human | S100A7 | 6278 | S100 calcium binding protein A7 | Suggest S100A7 polymorphisms are associated with allergic rhinitis in Swedish population | Human | NOS2 | 4843 | nitric oxide synthase 2, inducible | Increased expression of iNOS might have a role in the development of allergic inflammation in upper and lower airways and in comorbidity of allergic rhinitis and asthma | Human | MBL2 | 4153 | mannose-binding lectin (protein C) 2, soluble | Carriers of MBL gene variant alleles (MBLva) might be one of the host-related genetic factors involved in atopic disorders, namely allergic rhinitis | Human | IL18 | 3606 | interleukin 18 (interferon-gamma-inducing factor) | Interleukin-18 polymorphisms are associated with allergic rhinitis Title:Polymorphisms in the IL 18 gene are associated with specific sensitization to common allergens and allergic rhinitis.|Association:Y|Conclusion:IL18 might be responsible for the linkage effects seen in the chromosomal region 11q22, which has been found previously with the phenotype sensitization to mite allergen. Thus a suspected direct role of IL18 in the pathogenesis of atopy has been strengthened by the presence of 8 common SNPs in the promoter regions of IL18. | Human | IL13 | 3596 | interleukin 13 | Our results suggest that the IL-13 exon 4 G2044A polymorphism confers susceptibility to the development of allergic rhinitis in Koreans, whereas the IL-4Ralpha Gln551Arg polymorphism is not related to allergic rhinitis Title:A common IL-13 Arg130Gln single nucleotide polymorphism among Chinese atopy patients with allergic rhinitis.|Association:Y|Conclusion:Thus, our results suggest a possible involvement of IL-13 SNPs in the regulation of IgE production in response to allergens in this Chinese population. There is a common IL-13 Arg130Gln single nucleotide polymorphism among Chinese atopy patients with allergic rhinitis | Human | IL10 | 3586 | interleukin 10 | Title:Association between TNF-alpha and TGF-beta genotypes in infants and parental history of allergic rhinitis and asthma.|Association:Not Found|Conclusion:These results suggest a role for TNF-alpha and TGF-beta1 genotypes in the pathogenesis of allergic rhinitis and asthma, respectively. If confirmed by future studies, cytokine genotyping may be a useful tool for identifying at-risk infants who may benefit from the selective use of preventative and/or early intervention treatments for these disorders. | Human | IL6 | 3569 | interleukin 6 (interferon, beta 2) | Title:Association between TNF-alpha and TGF-beta genotypes in infants and parental history of allergic rhinitis and asthma.|Association:Not Found|Conclusion:These results suggest a role for TNF-alpha and TGF-beta1 genotypes in the pathogenesis of allergic rhinitis and asthma, respectively. If confirmed by future studies, cytokine genotyping may be a useful tool for identifying at-risk infants who may benefit from the selective use of preventative and/or early intervention treatments for these disorders. | Human | IFNG | 3458 | interferon, gamma | Title:Association between TNF-alpha and TGF-beta genotypes in infants and parental history of allergic rhinitis and asthma.|Association:Y|Conclusion:These results suggest a role for TNF-alpha and TGF-beta1 genotypes in the pathogenesis of allergic rhinitis and asthma, respectively. If confirmed by future studies, cytokine genotyping may be a useful tool for identifying at-risk infants who may benefit from the selective use of preventative and/or early intervention treatments for these disorders. | Human | HMOX1 | 3162 | heme oxygenase (decycling) 1 | expression of HO-1, but not HO-2, was upregulated within the nasal tissues in allergic rhinitis inflammation, and understanding the induction of HO-1 expression may provide for better management of allergic rhinitis that involves oxidative stress | Human | HLA-G | 3135 | | Soluble HLA-G serum level is significantly increased in allergic rhinitis patients with pollen allergy |
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