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Details
Link-It Detail - Disease - AIDS Dementia Complex
Debug Stats
  • ### Total Build Time: 38 ms 34.736 KB
  • CONCEPT_NAME gt=7 ms Completed: 7 ms rowSize= 417 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 701 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=4 ms Completed: 4 ms rowSize= 976 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 10.461 KB
  • CONCEPT_RELATIONSHIPS gt=21 ms Completed: 21 ms rowSize= 13.778 KB
  • CONCEPT_GENES gt=5 ms Completed: 5 ms rowSize= 7.078 KB
  • CONCEPT_XREFS gt=0 Completed: 0 ms rowSize= 1.155 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (2)
AIDS Dementia Complex C0001849
ACQUIRED IMMUNE DEFIC SYNDROME DEMENTIA COMPLEX
Definition (1)
A neurologic condition associated with the ACQUIRED IMMUNODEFICIENCY SYNDROME and characterized by impaired concentration and memory, slowness of hand movements, ATAXIA, incontinence, apathy, and gait difficulties associated with HIV-1 viral infection of the central nervous system. Pathologic examination of the brain reveals white matter rarefaction, perivascular infiltrates of lymphocytes, foamy macrophages, and multinucleated giant cells. (From Adams et al., Principles of Neurology, 6th ed, pp760-1; N Engl J Med, 1995 Apr 6;332(14):934-40)
Semantic Types (1)
Disease or Syndrome (T047)
Parents (2)
img HIV Infections C0019693
img Dementia C0497327
Ancestral Roots
RootRoot Plus OneDepthParent
img Bacterial Infections and Mycoses C0004615img Infection C00213116img HIV Infections C0019693
img Virus Diseases C0042769img Sexually Transmitted Diseases C00369165img HIV Infections C0019693
img Male Urogenital Diseases C1720894img Genital Diseases, Male C00174126img HIV Infections C0019693
img Female Urogenital Diseases and Pregnancy Complications C1720765img Female Urogenital Diseases C17208877img HIV Infections C0019693
img Immune System Diseases C0021053img Immunologic Deficiency Syndromes C00210514img HIV Infections C0019693
img Virus Diseases C0042769img RNA Virus Infections C00356906img HIV Infections C0019693
img Mental Disorders C0004936img Delirium, Dementia, Amnestic, Cognitive Disorders C00292274img Dementia C0497327
img Nervous System Diseases C0027765img Central Nervous System Diseases C00076825img Dementia C0497327
Relationships (54)

Relation Types:
diso_​to_​anat : 16
diso_​to_​chem : 9
diso_​to_​diso : 26
diso_​to_​phen : 2
diso_​to_​phys : 1


Relationships:
none : 44
associated_​with : 1
clinically_​similar : 1
is_​associated_​disease_​of : 1
is_​finding_​of_​disease : 1
isa : 2
location_​of : 1
permuted_​term_​of : 1
use : 2
Page Size
Current 25
  Page 1 of 3
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO115img HIV Infections C0019693
DISO_to_ANAT68img Brain C0006104
DISO_to_DISO65img HIV Infections C0019693
DISO_to_ANAT53img Brain C0006104
DISO_to_DISO42img Complication Aspects C1171258
DISO_to_ANAT40img Neurons C0027882
DISO_to_DISO39img Cognition Disorders C0009241
DISO_to_DISO37img Complication Aspects C1171258
DISO_to_ANAT31img Macrophages C0024432
DISO_to_DISO31img Acquired Immunodeficiency Syndrome C0001175
DISO_to_CHEM30img AIDS Drugs C0376565
DISO_to_DISO30img Cognition Disorders C0009241
DISO_to_PHEN28img genetic aspects C0017399
DISO_to_CHEM24img AIDS Drugs C0376565
DISO_to_DISO24img Acquired Immunodeficiency Syndrome C0001175
DISO_to_PHEN23img genetic aspects C0017399
DISO_to_ANAT21img Neurons C0027882
DISO_to_ANAT20img In Blood C0005768
DISO_to_ANAT19img Gitter cell C0206116
DISO_to_ANAT18img In Blood C0005768
DISO_to_ANAT18img Macrophages C0024432
DISO_to_ANAT16img Astrocytes C0004112
DISO_to_CHEM14img Agents, Neuroprotective C0242912
DISO_to_CHEM14img ENV GLYCOPROTEIN GP120 HIV C0019691
DISO_to_CHEM14img HIV Transacting Transcription Protein C0040623
Genes (6)

Species:
human : 6
SpeciesGeneGeneIdGene NameEvidence
HumanGLS227165glutaminase 2 (liver, mitochondrial)
img GENERIF, Score=913, Pubmed Id: 18088378, UMLKSK CUI: C0001849
HumanCXCR47852chemokine (C-X-C motif) receptor 4
img GENERIF, Score=1000, Pubmed Id: 17888880, UMLKSK CUI: C0001849
HumanTP537157tumor protein p53
img GENERIF, Score=708, Pubmed Id: 18040854, UMLKSK CUI: C0001849
HumanCCL26347chemokine (C-C motif) ligand 2
img GENERIF, Score=1000, Pubmed Id: 18508485, UMLKSK CUI: C0001849
HumanPLAUR5329plasminogen activator, urokinase receptor
img GENERIF, Score=1000, Pubmed Id: 15122709, UMLKSK CUI: C0001849
HumanNOS24843nitric oxide synthase 2, inducible
img GENERIF, Score=913, Pubmed Id: 12167619, UMLKSK CUI: C0001849
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0001849AIDS Dementia Complex0self