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Details
Link-It Detail - Disease - Adrenal Gland Diseases
Debug Stats
  • ### Total Build Time: 50 ms 38.473 KB
  • CONCEPT_NAME gt=11 ms Completed: 11 ms rowSize= 342 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 1.103 KB
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 561 bytes
  • CONCEPT_CHILDREN gt=3 ms Completed: 3 ms rowSize= 2.283 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 1.119 KB
  • CONCEPT_RELATIONSHIPS gt=16 ms Completed: 16 ms rowSize= 13.700 KB
  • CONCEPT_GENES gt=19 ms Completed: 19 ms rowSize= 18.019 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.156 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Adrenal Gland Diseases C0001621
Definition (1)

Your adrenal, or suprarenal, glands are located on the top of each kidney. These glands produce hormones that you can't live without, including sex hormones and cortisol, which helps you respond to stress and has many other functions.

Adrenal disorders can cause your adrenal glands to make too much or not enough hormones. With Cushing's syndrome, there's too much cortisol, while with Addison's disease, there is too little. Some people are born unable to make enough cortisol. Tumors can also cause disorders in your adrenal glands. Bleeding and infection can cause an adrenal gland problem that can be fatal without quick treatment.

Treatment depends on which problem you have. Surgery or medicines can treat many adrenal gland disorders.

Semantic Types (1)
Disease or Syndrome (T047)
Parents (1)
img Endocrine System Diseases C0014130
Children (5)
img Adrenal Gland Neoplasms C0001624
img Adrenal Hyperplasia, Congenital C0001627
img Adrenal Insufficiency C0001623
img Adrenocortical Hyperfunction C0001622
img Adrenal Cortex Diseases C0001614
Ancestral Roots
RootRoot Plus OneDepthParent
img Endocrine System Diseases C00141302img Endocrine System Diseases C0014130
Relationships (75)

Relation Types:
diso_​to_​anat : 6
diso_​to_​chem : 5
diso_​to_​diso : 61
diso_​to_​phen : 2
diso_​to_​phys : 1


Relationships:
none : 28
associated_​with : 1
classifies : 1
is_​associated_​anatomic_​site_​of : 2
isa : 26
location_​of : 1
mapped_​to : 9
may_​diagnose : 2
related_​to : 5
Page Size
Current 25
  Page 1 of 3
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO74img Complication Aspects C1171258
DISO_to_DISO58img Hemorrhage C0019080
DISO_to_DISO52img Cyst C0010709
DISO_to_DISO50img Complication Aspects C1171258
DISO_to_DISO45img Hemorrhage C0019080
DISO_to_ANAT44img Adrenal Glands C0001625
DISO_to_ANAT42img Adrenal Glands C0001625
DISO_to_DISO30img Cyst C0010709
DISO_to_DISO29img Adrenal Gland Neoplasms C0001624
DISO_to_PHEN20img genetic aspects C0017399
DISO_to_DISO19img Adrenal Gland Neoplasms C0001624
DISO_to_PHEN19img genetic aspects C0017399
DISO_to_DISO16img Hematoma C0018944
DISO_to_ANAT15img In Blood C0005768
DISO_to_DISO15img Hypertension C0020538
DISO_to_DISO14img Hematoma C0018944
DISO_to_DISO12img Abscess C0000833
DISO_to_DISO12img Histoplasmosis C0019655
DISO_to_DISO11img Endocrine Tuberculoses C0041310
DISO_to_CHEM10img Adrenocorticotropic Hormone C0001655
DISO_to_CHEM10img GLUCOCORTICOIDS C0017710
DISO_to_DISO10img Echinococcosis C0013502
DISO_to_DISO10img chemically induced C0007994
DISO_to_DISO9img Kidney Diseases C0022658
DISO_to_CHEM8img Hydrocortisone C0020268
Genes (167)

Species:
human : 167
Page Size
Current 25
  Page 1 of 7
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanLOC100507436100507436
INFERRED, Score=800, UMLKSK CUI: C0001621
HumanCCR2729230chemokine (C-C motif) receptor 2
INFERRED, Score=800, UMLKSK CUI: C0001621
HumanMIR212406994microRNA 212
INFERRED, Score=800, UMLKSK CUI: C0001621
HumanH19283120H19, imprinted maternally expressed transcript (non-protein coding)
INFERRED, Score=800, UMLKSK CUI: C0001621
HumanNEWENTRY192343Record to support submission of GeneRIFs for a gene not in Gene (human; man).
INFERRED, Score=800, UMLKSK CUI: C0001621
HumanEXOSC6118460exosome component 6
INFERRED, Score=800, UMLKSK CUI: C0001621
HumanUCN3114131urocortin 3
INFERRED, Score=800, UMLKSK CUI: C0001621
HumanINHBE83729inhibin, beta E
INFERRED, Score=800, UMLKSK CUI: C0001621
HumanACSBG281616acyl-CoA synthetase bubblegum family member 2
INFERRED, Score=800, UMLKSK CUI: C0001621
HumanRBAK57786RB-associated KRAB zinc finger
INFERRED, Score=800, UMLKSK CUI: C0001621
HumanAKR1B1057016aldo-keto reductase family 1, member B10 (aldose reductase)
INFERRED, Score=800, UMLKSK CUI: C0001621
HumanPEX2655670peroxisomal biogenesis factor 26
INFERRED, Score=800, UMLKSK CUI: C0001621
HumanCYP2W154905cytochrome P450, family 2, subfamily W, polypeptide 1
INFERRED, Score=800, UMLKSK CUI: C0001621
HumanKRT2054474keratin 20
INFERRED, Score=800, UMLKSK CUI: C0001621
HumanDCUN1D154165DCN1, defective in cullin neddylation 1, domain containing 1
INFERRED, Score=800, UMLKSK CUI: C0001621
HumanGHRL51738ghrelin/obestatin prepropeptide
INFERRED, Score=800, UMLKSK CUI: C0001621
HumanPDE11A50940phosphodiesterase 11A
INFERRED, Score=800, UMLKSK CUI: C0001621
HumanPTPN2226191protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
INFERRED, Score=800, UMLKSK CUI: C0001621
HumanCLEC16A23274C-type lectin domain family 16, member A
INFERRED, Score=800, UMLKSK CUI: C0001621
HumanACSBG123205acyl-CoA synthetase bubblegum family member 1
INFERRED, Score=800, UMLKSK CUI: C0001621
HumanUTS210911urotensin 2
INFERRED, Score=800, UMLKSK CUI: C0001621
HumanNES10763nestin
INFERRED, Score=800, UMLKSK CUI: C0001621
HumanMSLN10232mesothelin
INFERRED, Score=800, UMLKSK CUI: C0001621
HumanBCAP3110134B-cell receptor-associated protein 31
INFERRED, Score=800, UMLKSK CUI: C0001621
HumanNCOR29612nuclear receptor corepressor 2
INFERRED, Score=800, UMLKSK CUI: C0001621
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0001621Adrenal Gland Diseases0self