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Details
Link-It Detail - Disease - Acidosis, Lactic
Debug Stats
  • ### Total Build Time: 188 ms 42.960 KB
  • CONCEPT_NAME gt=12 ms Completed: 12 ms rowSize= 375 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 352 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=23 ms Completed: 23 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=4 ms Completed: 4 ms rowSize= 544 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=1 ms Completed: 1 ms rowSize= 1.508 KB
  • CONCEPT_RELATIONSHIPS gt=104 ms Completed: 104 ms rowSize= 13.020 KB
  • CONCEPT_GENES gt=41 ms Completed: 41 ms rowSize= 25.822 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.150 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (2)
Acidosis, Lactic C0001125
ACIDOSIS LACTIC
Definition (1)
acidosis caused by accumulation of lactic acid more rapidly than it can be metabolized; may occur spontaneously or in association with diseases such as diabetes mellitus, leukemia, or liver failure.
Semantic Types (1)
Disease or Syndrome (T047)
Parents (1)
img Acidosis C0001122
Ancestral Roots
RootRoot Plus OneDepthParent
img Nutritional and Metabolic Diseases C0028715img Metabolic Diseases C00255175img Acidosis C0001122
Relationships (57)

Relation Types:
diso_​to_​anat : 3
diso_​to_​chem : 23
diso_​to_​diso : 27
diso_​to_​phen : 2
diso_​to_​phys : 2


Relationships:
none : 42
associated_​with : 2
isa : 4
mapped_​to : 7
use : 2
Page Size
Current 25
  Page 1 of 3
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO181img chemically induced C0007994
DISO_to_DISO168img chemically induced C0007994
DISO_to_CHEM104img 1,1-Dimethylbiguanide C0025598
DISO_to_CHEM90img Agents, Antihyperglycemic C0020616
DISO_to_CHEM71img Agents, Antihyperglycemic C0020616
DISO_to_CHEM68img 1,1-Dimethylbiguanide C0025598
DISO_to_ANAT63img In Blood C0005768
DISO_to_DISO63img HIV Infections C0019693
DISO_to_ANAT52img In Blood C0005768
DISO_to_CHEM52img Lactic Acid C0064582
DISO_to_CHEM41img Reverse Transcriptase Inhibitors C0282519
DISO_to_CHEM36img AIDS Drugs C0376565
DISO_to_DISO32img Complication Aspects C1171258
DISO_to_CHEM31img Lactic Acid C0064582
DISO_to_DISO31img Diabetes Mellitus, Non-Insulin-Dependent C0011860
DISO_to_PHEN29img genetic aspects C0017399
DISO_to_DISO28img Diabetes Mellitus, Non-Insulin-Dependent C0011860
DISO_to_DISO26img Complication Aspects C1171258
DISO_to_DISO21img HIV Infections C0019693
DISO_to_DISO18img Acute kidney injury C2609414
DISO_to_CHEM16img AIDS Drugs C0376565
DISO_to_CHEM16img Lactates C0022924
DISO_to_PHEN15img genetic aspects C0017399
DISO_to_ANAT13img Muscle, Skeletal C0242692
DISO_to_DISO13img Acute kidney injury C2609414
Genes (52)

Species:
human : 52
Page Size
Current 25
  Page 1 of 3
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanNDUFS7374291NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)
img OMIM, Score=1000, UMLKSK CUI: C0001125
HumanC8orf38137682
img OMIM, Score=1000, UMLKSK CUI: C0001125
HumanNDUFAF291942NADH dehydrogenase (ubiquinone) complex I, assembly factor 2
img OMIM, Score=1000, UMLKSK CUI: C0001125
HumanPUS180324pseudouridylate synthase 1
img OMIM, Score=1000, UMLKSK CUI: C0001125
HumanC20orf779133
img OMIM, Score=1000, UMLKSK CUI: C0001125
HumanC10orf256652chromosome 10 open reading frame 2
img OMIM, Score=1000, UMLKSK CUI: C0001125
HumanPDP154704pyruvate dehyrogenase phosphatase catalytic subunit 1
img OMIM, Score=1000, UMLKSK CUI: C0001125
HumanMRPS1651021mitochondrial ribosomal protein S16
img OMIM, Score=1000, UMLKSK CUI: C0001125
HumanNDUFAF429078NADH dehydrogenase (ubiquinone) complex I, assembly factor 4
img OMIM, Score=1000, UMLKSK CUI: C0001125
HumanUQCRQ27089ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa
img OMIM, Score=1000, UMLKSK CUI: C0001125
HumanISCU23479iron-sulfur cluster assembly enzyme
img GENERIF, Score=1000, Pubmed Id: 18296749, UMLKSK CUI: C0001125
HumanLRPPRC10128leucine-rich pentatricopeptide repeat containing
img OMIM, Score=1000, UMLKSK CUI: C0001125
HumanTSFM10102Ts translation elongation factor, mitochondrial
img OMIM, Score=1000, UMLKSK CUI: C0001125
HumanSCO29997SCO2 cytochrome c oxidase assembly protein
img OMIM, Score=1000, UMLKSK CUI: C0001125
HumanSUCLA28803succinate-CoA ligase, ADP-forming, beta subunit
img OMIM, Score=1000, UMLKSK CUI: C0001125
HumanSUCLG18802succinate-CoA ligase, alpha subunit
img OMIM, Score=1000, UMLKSK CUI: C0001125
HumanPDHX8050pyruvate dehydrogenase complex, component X
img OMIM, Score=1000, UMLKSK CUI: C0001125
HumanUQCRB7381ubiquinol-cytochrome c reductase binding protein
img OMIM, Score=1000, UMLKSK CUI: C0001125
HumanTNF7124tumor necrosis factor
img GENERIF, Score=1000, Pubmed Id: 12078789, UMLKSK CUI: C0001125
HumanTK27084thymidine kinase 2, mitochondrial
img OMIM, Score=1000, UMLKSK CUI: C0001125
HumanSURF16834surfeit 1
img OMIM, Score=1000, UMLKSK CUI: C0001125
HumanSDHA6389succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
img OMIM, Score=1000, UMLKSK CUI: C0001125
img OMIM, Score=1000, UMLKSK CUI: C0001125
HumanSLC25A35250solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
img GENERIF, Score=1000, Pubmed Id: 17273968, UMLKSK CUI: C0001125
HumanPDHA15160pyruvate dehydrogenase (lipoamide) alpha 1
img OMIM, Score=1000, UMLKSK CUI: C0001125
img OMIM, Score=1000, UMLKSK CUI: C0001125
img OMIM, Score=1000, UMLKSK CUI: C0001125
HumanPCCB5096propionyl CoA carboxylase, beta polypeptide
img OMIM, Score=1000, UMLKSK CUI: C0001125
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0001125Acidosis, Lactic0self