Logo arc image image
GATACA
  • Pin/Unpin Search
  • Pin/Unpin Details
Status:
Global Actions
Concepts: 0 (0)   Selected: 0 (0
Clear All Selections
 
Search
Text Search Results
Text Search Query:
none
Text Search Options:
none

Guided Help

Text Search Results
GraphTree Minimize or Maximize this Category
 Disease: 0
No results.
 Concepts (w/Genes): 0 (0)   Selected (w/genes): 0 (0)
GraphTree Minimize or Maximize this Category
 Anatomy: 0
No results.
 Concepts (w/Genes): 0 (0)   Selected (w/genes): 0 (0)
Minimize or Maximize this Category
 Gene: 0
No results.
 Concepts (w/Genes): 0 (0)   Selected (w/genes): 0 (0)
GraphTree Minimize or Maximize this Category
 Jax Mouse Phenotype: 0
No results.
 Concepts (w/Genes): 0 (0)   Selected (w/genes): 0 (0)
GraphTree Minimize or Maximize this Category
 Human Phenotype: 0
No results.
 Concepts (w/Genes): 0 (0)   Selected (w/genes): 0 (0)
GraphTree Minimize or Maximize this Category
 Gene Ontology: Biological Processes: 0
No results.
 Concepts (w/Genes): 0 (0)   Selected (w/genes): 0 (0)
GraphTree Minimize or Maximize this Category
 Gene Ontology: Cellular Component: 0
No results.
 Concepts (w/Genes): 0 (0)   Selected (w/genes): 0 (0)
GraphTree Minimize or Maximize this Category
 Gene Ontology: Molecular Function: 0
No results.
 Concepts (w/Genes): 0 (0)   Selected (w/genes): 0 (0)
Minimize or Maximize this Category
 Pathway: 0
No results.
 Concepts (w/Genes): 0 (0)   Selected (w/genes): 0 (0)
GraphTree Minimize or Maximize this Category
 Drug: 0
No results.
 Concepts (w/Genes): 0 (0)   Selected (w/genes): 0 (0)
Minimize or Maximize this Category
 Genomic Expression Atlas --
      Microarray Datasets: 0
No results.
 Concepts (w/Genes): 0 (0)   Selected (w/genes): 0 (0)
Minimize or Maximize this Category
 PubMed: 0
No results.
 Concepts (w/Genes): 0 (0)   Selected (w/genes): 0 (0)
GraphTree Minimize or Maximize this Category
 CoExpression Atlas: 0
No results.
 Concepts (w/Genes): 0 (0)   Selected (w/genes): 0 (0)
Minimize or Maximize this Category
 CoExpression: 0
No results.
 Concepts (w/Genes): 0 (0)   Selected (w/genes): 0 (0)
Minimize or Maximize this Category
 Interactions: 0
No results.
 Concepts (w/Genes): 0 (0)   Selected (w/genes): 0 (0)
Details
Link-It Detail - Disease - Acantholysis
Debug Stats
  • ### Total Build Time: 205 ms 26.099 KB
  • CONCEPT_NAME gt=7 ms Completed: 7 ms rowSize= 364 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 361 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=107 ms Completed: 107 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=11 ms Completed: 11 ms rowSize= 1,004 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=12 ms Completed: 12 ms rowSize= 2.821 KB
  • CONCEPT_RELATIONSHIPS gt=46 ms Completed: 46 ms rowSize= 8.889 KB
  • CONCEPT_GENES gt=20 ms Completed: 20 ms rowSize= 11.335 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.146 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (2)
Acantholysis C0000887
Acantholyses
Definition (1)
Separation of the prickle cells of the stratum spinosum of the epidermis, resulting in atrophy of the prickle cell layer. It is seen in diseases such as pemphigus vulgaris (see PEMPHIGUS) and DARIER DISEASE.
Semantic Types (1)
Pathologic Function (T046)
Parents (2)
img Skin Diseases, Vesiculobullous C0037275
img Pathologic Processes C0030660
Ancestral Roots
RootRoot Plus OneDepthParent
img Skin and Connective Tissue Diseases C0175166img Skin Diseases C00372744img Skin Diseases, Vesiculobullous C0037275
img Pathological Conditions, Signs and Symptoms C0039058img Pathologic Processes C00306603img Pathologic Processes C0030660
Relationships (20)

Relation Types:
diso_​to_​anat : 1
diso_​to_​diso : 18
diso_​to_​phen : 1


Relationships:
none : 12
associated_​with : 1
disease_​has_​finding : 5
mapped_​to : 1
permuted_​term_​of : 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO21img Pemphigus C0030807
DISO_to_DISO15img Pemphigus C0030807
DISO_to_ANAT10img Keratinocytes C0022567
DISO_to_DISO10img Complication Aspects C1171258
DISO_to_DISO10img Keratosis C0022593
DISO_to_DISO9img Complication Aspects C1171258
DISO_to_DISO8img Ichthyosis C0020757
DISO_to_DISO7img Carcinoma, Squamous Cell C0007137
DISO_to_DISO7img Cutaneous tumor C0037286
DISO_to_DISO7img Keratosis C0022593
DISO_to_DISO7img chemically induced C0007994
DISO_to_PHEN7img genetic aspects C0017399
DISO_to_DISOpermuted_term_ofimg Acantholyses C0000887
DISO_to_DISOdisease_has_findingimg Acantholytic Acanthoma C1301270
DISO_to_DISOdisease_has_findingimg Acantholytic Squamous Cell Carcinoma of Skin C0345979
DISO_to_DISOassociated_withimg Bullous pemphigoid C0030805
DISO_to_DISOdisease_has_findingimg Dyskeratosis follicularis, isolated C0334063
DISO_to_DISOmapped_toimg Grover disease C0263325
DISO_to_DISOdisease_has_findingimg Laryngeal Acantholytic Squamous Cell Carcinoma C1708648
DISO_to_DISOdisease_has_findingimg Squamous Cell Breast Carcinoma, Acantholytic Variant C1519485
Genes (9)

Species:
human : 9
SpeciesGeneGeneIdGene NameEvidence
HumanTNF7124tumor necrosis factor
img GENERIF, Score=1000, Pubmed Id: 17101499, UMLKSK CUI: C0000887
img GENERIF, Score=1000, Pubmed Id: 12930304, UMLKSK CUI: C0000887
HumanPLAU5328plasminogen activator, urokinase
img GENERIF, Score=1000, Pubmed Id: 12930304, UMLKSK CUI: C0000887
HumanMMP94318matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
img GENERIF, Score=827, Pubmed Id: 17311292, UMLKSK CUI: C0000887
HumanIL1A3552interleukin 1, alpha
img GENERIF, Score=1000, Pubmed Id: 12930304, UMLKSK CUI: C0000887
HumanDSP1832desmoplakin
img OMIM, Score=1000, UMLKSK CUI: C0000887
img OMIM, Score=1000, UMLKSK CUI: C0000887
HumanCHRNA71139cholinergic receptor, nicotinic, alpha 7 (neuronal)
img GENERIF, Score=861, Pubmed Id: 18073210, UMLKSK CUI: C0000887
HumanCHRM11128cholinergic receptor, muscarinic 1
img GENERIF, Score=861, Pubmed Id: 18073210, UMLKSK CUI: C0000887
HumanATP2A2488ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
img OMIM, Score=1000, UMLKSK CUI: C0000887
img OMIM, Score=1000, UMLKSK CUI: C0000887
HumanFASLG356Fas ligand (TNF superfamily, member 6)
img GENERIF, Score=1000, Pubmed Id: 17101499, UMLKSK CUI: C0000887
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0000887Acantholysis0self