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Details
Link-It Detail - Disease - Abortion, Spontaneous
Debug Stats
  • ### Total Build Time: 109 ms 47.729 KB
  • CONCEPT_NAME gt=3 ms Completed: 3 ms rowSize= 390 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
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  • CONCEPT_GENES gt=16 ms Completed: 16 ms rowSize= 24.234 KB
  • CONCEPT_XREFS gt=3 ms Completed: 3 ms rowSize= 1.155 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (2)
Abortion, Spontaneous C0000786
Spontaneous abortion
Definition (1)

A miscarriage is the loss of pregnancy from natural causes before the 20th week of pregnancy. Most miscarriages occur very early in the pregnancy, often before a woman even knows she is pregnant. There are many different causes for a miscarriage. In most cases, there is nothing you can do to prevent a miscarriage.

Factors that may contribute to miscarriage include

  • A genetic problem with the fetus. This is the most common cause in the first trimester.
  • Problems with the uterus or cervix. These contribute in the second trimester.
  • Polycystic ovary syndrome

Signs of a miscarriage can include vaginal spotting or bleeding, abdominal pain or cramping, and fluid or tissue passing from the vagina. Although vaginal bleeding is a common symptom of miscarriage, many women have spotting early in their pregnancy but do not miscarry. But if you are pregnant and have bleeding or spotting, contact your health care provider immediately.

Women who miscarry early in their pregnancy usually do not need any treatment. In some cases, you may need a procedure called a dilatation and curettage (D&C) to remove tissue remaining in the uterus.

Counseling may help you cope with your grief. Later, if you do decide to try again, work closely with your health care provider to lower the risks. Many women who have a miscarriage go on to have healthy babies.

NIH: National Institute of Child Health and Human Development

Semantic Types (1)
Disease or Syndrome (T047)
Parents (1)
img Pregnancy Complications C0032962
Children (7)
img Embryo Loss C0752351
img Abortion, Missed C0000814
img Abortion, Septic C0000817
img Abortion, Threatened C0000821
img Abortion, Incomplete C0000810
img Abortion, Veterinary C0000823
img Abortion, Habitual C0000809
Ancestral Roots
RootRoot Plus OneDepthParent
img Female Urogenital Diseases and Pregnancy Complications C1720765img Pregnancy Complications C00329623img Pregnancy Complications C0032962
Relationships (164)

Relation Types:
diso_​to_​anat : 15
diso_​to_​chem : 38
diso_​to_​diso : 99
diso_​to_​gene : 1
diso_​to_​phen : 2
diso_​to_​phys : 9


Relationships:
none : 91
classified_​as : 29
has_​single_​level_​category : 1
induces : 14
isa : 14
may_​prevent : 5
may_​treat : 5
parent_​is_​cdrh : 1
related_​to : 4
Page Size
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Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_PHEN162img genetic aspects C0017399
DISO_to_PHEN92img genetic aspects C0017399
DISO_to_DISO72img chemically induced C0007994
DISO_to_ANAT67img In Blood C0005768
DISO_to_DISO62img Pregnancy Outcome C0032972
DISO_to_ANAT57img In Blood C0005768
DISO_to_DISO48img Stillbirth C0595939
DISO_to_DISO42img Fetal Death C0015927
DISO_to_DISO41img OUTCOME PREGN C0032972
DISO_to_DISO38img Pregnancy Complications C0032962
DISO_to_DISO34img Female infertility C0021361
DISO_to_DISO34img chemically induced C0007994
DISO_to_DISO33img Pregnancy Complications C0032962
DISO_to_DISO33img Pregnancy Complications, Infectious C0032965
DISO_to_DISO29img COMPL PREGN INFECT C0032965
DISO_to_DISO28img Abortion, Habitual C0000809
DISO_to_DISO28img Fetal Death C0015927
DISO_to_DISO28img Premature Birth C0151526
DISO_to_ANAT27img Placenta C0032043
DISO_to_ANAT24img Uterus C0042149
DISO_to_CHEM23img (11alpha,13E)-(+-)-11,16-Dihydroxy-16-methyl-9-oxo-prost-13-en-1-oic Acid Methyl Ester C0085174
DISO_to_CHEM23img Misoprostol C0085174
DISO_to_DISO23img Chromosome Aberrations C0008625
DISO_to_ANAT22img Decidua C0011106
DISO_to_CHEM22img Abortifacient Agents, Non Steroidal C0000783
Genes (66)

Species:
human : 66
Page Size
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Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanH19283120H19, imprinted maternally expressed transcript (non-protein coding)
img GENERIF, Score=861, Pubmed Id: 18573128, UMLKSK CUI: C0000786
HumanNCR3259197natural cytotoxicity triggering receptor 3
img GENERIF, Score=1000, Pubmed Id: 18023431, UMLKSK CUI: C0000786
HumanSYCP350511synaptonemal complex protein 3
INFERRED, Score=800, UMLKSK CUI: C0000786
HumanRAI110743retinoic acid induced 1
INFERRED, Score=800, UMLKSK CUI: C0000786
HumanGNLY10578granulysin
img GENERIF, Score=1000, Pubmed Id: 18688023, UMLKSK CUI: C0000786
HumanPROCR10544protein C receptor, endothelial
INFERRED, Score=800, UMLKSK CUI: C0000786
HumanNCR19437natural cytotoxicity triggering receptor 1
img GENERIF, Score=1000, Pubmed Id: 18023431, UMLKSK CUI: C0000786
HumanNCR29436natural cytotoxicity triggering receptor 2
img GENERIF, Score=1000, Pubmed Id: 18023431, UMLKSK CUI: C0000786
HumanPROZ8858protein Z, vitamin K-dependent plasma glycoprotein
INFERRED, Score=800, UMLKSK CUI: C0000786
HumanVEGFA7422vascular endothelial growth factor A
INFERRED, Score=800, UMLKSK CUI: C0000786
HumanTYMS7298thymidylate synthetase
img GENERIF, Score=901, Pubmed Id: 15985285, UMLKSK CUI: C0000786
HumanTP537157tumor protein p53
img GENERIF, Score=1000, Pubmed Id: 16569330, UMLKSK CUI: C0000786
HumanTNFRSF1A7132tumor necrosis factor receptor superfamily, member 1A
img GENERIF, Score=1000, Pubmed Id: 16859822, UMLKSK CUI: C0000786
HumanTNF7124tumor necrosis factor
INFERRED, Score=800, UMLKSK CUI: C0000786
HumanTLR27097toll-like receptor 2
INFERRED, Score=800, UMLKSK CUI: C0000786
HumanTHPO7066thrombopoietin
img GENERIF, Score=1000, Pubmed Id: 17706203, UMLKSK CUI: C0000786
HumanTHBD7056thrombomodulin
INFERRED, Score=800, UMLKSK CUI: C0000786
HumanTGFB27042transforming growth factor, beta 2
INFERRED, Score=800, UMLKSK CUI: C0000786
HumanTCN26948transcobalamin II
img GAD, Score=1000, Pubmed Id: 12456598, UMLKSK CUI: C0000786
HumanSELP6403selectin P (granule membrane protein 140kDa, antigen CD62)
img GENERIF, Score=901, Pubmed Id: 18550060, UMLKSK CUI: C0000786
HumanSELL6402selectin L
INFERRED, Score=800, UMLKSK CUI: C0000786
HumanMAPK95601mitogen-activated protein kinase 9
INFERRED, Score=800, UMLKSK CUI: C0000786
HumanPOMC5443proopiomelanocortin
img GENERIF, Score=1000, Pubmed Id: 16136012, UMLKSK CUI: C0000786
HumanPGR5241progesterone receptor
img GENERIF, Score=1000, Pubmed Id: 12009358, UMLKSK CUI: C0000786
HumanPAPPA5069pregnancy-associated plasma protein A, pappalysin 1
img GENERIF, Score=1000, Pubmed Id: 15305104, UMLKSK CUI: C0000786
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0000786Abortion, Spontaneous0self