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GATACA
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Details
Link-It Detail - Anatomy - 20S methylosome
Debug Stats
  • ### Total Build Time: 3 ms 7.203 KB
  • CONCEPT_NAME gt=0 Completed: 0 ms rowSize= 328 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 729 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 998 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 2.785 KB
  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 1.169 KB
  • CONCEPT_GENES gt=2 ms Completed: 2 ms rowSize= 45 bytes
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.149 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Anatomy (1)
20S methylosome C2612853
Definition (1)
A large (20 S) protein complex that possesses protein arginine methyltransferase activity and modifies specific arginines to dimethylarginines in the arginine- and glycine-rich domains of several spliceosomal Sm proteins, thereby targeting these proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein (snRNP) core particles. Proteins found in the methylosome include the methyltransferase JBP1 (PRMT5), pICln (CLNS1A), MEP50 (WDR77), and unmethylated forms of SM proteins that have RG domains. [PMID:11713266, PMID:11756452]
Parents (2)
img methyltransferase complex C2612852
img cytoplasm component C1820050
Ancestral Roots
RootRoot Plus OneDepthParent
img intracellular part C1820033img methyltransferase complex C26128523img methyltransferase complex C2612852
img intracellular part C1820033img cytoplasm component C18200503img cytoplasm component C1820050
Relationships (1)

Relation Types:
anat_​to_​anat : 1


Relationships:
mth_​expanded_​form_​of : 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
ANAT_to_ANATmth_expanded_form_ofimg 20S methylosome C2612853
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C261285320S methylosome0self