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Details
Link-It Detail - Anatomy - THO complex
Debug Stats
  • ### Total Build Time: 55 ms 7.222 KB
  • CONCEPT_NAME gt=7 ms Completed: 7 ms rowSize= 320 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 635 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=13 ms Completed: 13 ms rowSize= 548 bytes
  • CONCEPT_CHILDREN gt=13 ms Completed: 13 ms rowSize= 1,013 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 1.506 KB
  • CONCEPT_RELATIONSHIPS gt=15 ms Completed: 15 ms rowSize= 2.028 KB
  • CONCEPT_GENES gt=3 ms Completed: 3 ms rowSize= 45 bytes
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.146 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Anatomy (1)
THO complex C1325727
Definition (1)
The THO complex is a nuclear complex that is required for transcription elongation through genes containing tandemly repeated DNA sequences. The THO complex is also part of the TREX (TRanscription EXport) complex that is involved in coupling transcription to export of mRNAs to the cytoplasm. In S. cerevisiae, it is composed of four subunits: Hpr1p, Tho2p, Thp1p, and Mft1p, while the human complex is composed of 7 subunits. [GOC:krc, PMID:11060033, PMID:11979277, PMID:16983072]
Parents (1)
img nuclear part C1820036
Children (2)
img nucleoplasmic THO complex C2263054
img THO complex part of TREX complex C2263053
Ancestral Roots
RootRoot Plus OneDepthParent
img intracellular part C1820033img intracellular organelle part C18200524img nuclear part C1820036
Relationships (3)

Relation Types:
anat_​to_​anat : 3


Relationships:
isa : 2
mth_​expanded_​form_​of : 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
ANAT_to_ANATmth_expanded_form_ofimg THO complex C1325727
ANAT_to_ANATisaimg THO complex part of TREX complex C2263053
ANAT_to_ANATisaimg nucleoplasmic THO complex C2263054
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C1325727THO complex0self