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Details
Link-It Detail - Anatomy - Blood-Brain Barrier
Debug Stats
  • ### Total Build Time: 164 ms 37.984 KB
  • CONCEPT_NAME gt=2 ms Completed: 2 ms rowSize= 395 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 343 bytes
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  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
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  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=1 ms Completed: 1 ms rowSize= 3.627 KB
  • CONCEPT_RELATIONSHIPS gt=59 ms Completed: 59 ms rowSize= 13.853 KB
  • CONCEPT_GENES gt=96 ms Completed: 96 ms rowSize= 17.450 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.153 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Anatomy (2)
Blood-Brain Barrier C0005854
Blood - brain barrier anatomy
Definition (1)
Specialized non-fenestrated tightly-joined ENDOTHELIAL CELLS with TIGHT JUNCTIONS that form a transport barrier for certain substances between the cerebral capillaries and the BRAIN tissue.
Semantic Types (1)
Organ or Tissue Function (T042)
Parents (2)
img Cardiovascular System C0007226
img Brain C0006104
Ancestral Roots
RootRoot Plus OneDepthParent
img Cardiovascular System C00072262img Cardiovascular System C0007226
img Nervous System Part C1518256img Central Nervous System C09272324img Brain C0006104
img Nervous System C0027763img Central Nervous System C09272324img Brain C0006104
Relationships (176)

Relation Types:
anat_​to_​anat : 32
anat_​to_​chem : 70
anat_​to_​diso : 48
anat_​to_​phen : 3
anat_​to_​phys : 23


Relationships:
none : 171
gene_​product_​has_​associated_​anatomy : 2
has_​physical_​part_​of_​anatomic_​structure : 1
permuted_​term_​of : 1
use : 1
Page Size
Current 25
  Page 1 of 8
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Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
ANAT_to_PHYS495img physiological aspects C0031843
ANAT_to_ANAT354img Brain C0006104
ANAT_to_PHYS350img physiological aspects C0031843
ANAT_to_ANAT309img Brain C0006104
ANAT_to_ANAT204img Cell, Endothelial C0225336
ANAT_to_CHEM117img P-Glycoprotein C0242643
ANAT_to_ANAT112img Endothelium, Vascular C0014261
ANAT_to_ANAT96img Cell, Endothelial C0225336
ANAT_to_DISO93img Brain Ischemia C0007786
ANAT_to_PHYS92img Capillary Permeability C0006906
ANAT_to_CHEM86img P-Glycoprotein C0242643
ANAT_to_DISO86img Brain Neoplasms C0006118
ANAT_to_DISO76img Cerebrovascular accident C0038454
ANAT_to_ANAT73img Tight Junctions C0242358
ANAT_to_DISO73img Brain Edema C1527311
ANAT_to_DISO68img Alzheimer Disease C0002395
ANAT_to_PHYS68img Capillary Permeabilities C0006906
ANAT_to_ANAT66img Astrocytes C0004112
ANAT_to_DISO63img Brain Neoplasms C0006118
ANAT_to_ANAT62img Endothelium, Vascular C0014261
ANAT_to_CHEM55img Amyloid beta-Peptides C0078939
ANAT_to_CHEM52img Membrane Associated Proteins C0025252
ANAT_to_DISO52img Brain Ischemia C0007786
ANAT_to_CHEM51img ATP-Binding Cassette Transporters C0242738
ANAT_to_CHEM51img Agents, Neuroprotective C0242912
Genes (3985)

Species:
human : 3949
mouse : 36
Page Size
Current 25
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Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanTNNI37137troponin I type 3 (cardiac)
MousePAOX196743polyamine oxidase (exo-N4-amino)
MouseGOPC57120golgi-associated PDZ and coiled-coil motif containing
MouseSULF255959sulfatase 2
MouseSMOX54498spermine oxidase
MouseDLL128514delta-like 1 (Drosophila)
MouseABHD211057abhydrolase domain containing 2
MouseNES10763nestin
MouseHYOU110525hypoxia up-regulated 1
MouseOLIG210215oligodendrocyte lineage transcription factor 2
MousePLAA9373phospholipase A2-activating protein
MouseHYAL28692hyaluronoglucosaminidase 2
MouseEZR7430ezrin
MouseTHBS27058thrombospondin 2
MouseSOD16647superoxide dismutase 1, soluble
MouseSFRP26423secreted frizzled-related protein 2
MouseSAG6295S-antigen; retina and pineal gland (arrestin)
MouseRBP35949retinol binding protein 3, interstitial
MouseRAD515888RAD51 recombinase
MouseOSM5008oncostatin M
MouseNDN4692necdin, melanoma antigen (MAGE) family member
MouseMLF14291myeloid leukemia factor 1
MouseMARCKS4082myristoylated alanine-rich protein kinase C substrate
MouseLGALS3BP3959lectin, galactoside-binding, soluble, 3 binding protein
MouseINSR3643insulin receptor
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0005854Blood-Brain Barrier0self