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Details
Link-It Detail - Anatomy - Basement Membrane
Debug Stats
  • ### Total Build Time: 224 ms 39.729 KB
  • CONCEPT_NAME gt=2 ms Completed: 2 ms rowSize= 332 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 708 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 175 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=7 ms Completed: 7 ms rowSize= 979 bytes
  • CONCEPT_CHILDREN gt=4 ms Completed: 4 ms rowSize= 1,000 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=5 ms Completed: 5 ms rowSize= 2.737 KB
  • CONCEPT_RELATIONSHIPS gt=57 ms Completed: 57 ms rowSize= 14.689 KB
  • CONCEPT_GENES gt=144 ms Completed: 144 ms rowSize= 18.004 KB
  • CONCEPT_XREFS gt=5 ms Completed: 5 ms rowSize= 1.151 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Anatomy (1)
Basement Membrane C0004799
Definition (1)
A darkly stained mat-like EXTRACELLULAR MATRIX (ECM) that separates cell layers, such as EPITHELIUM from ENDOTHELIUM or a layer of CONNECTIVE TISSUE. The ECM layer that supports an overlying EPITHELIUM or ENDOTHELIUM is called basal lamina. Basement membrane (BM) can be formed by the fusion of either two adjacent basal laminae or a basal lamina with an adjacent reticular lamina of connective tissue. BM, composed mainly of TYPE IV COLLAGEN; glycoprotein LAMININ; and PROTEOGLYCAN, provides barriers as well as channels between interacting cell layers.
Semantic Types (1)
Tissue (T024)
Parents (2)
img Epithelium C0014609
img Epithelium Part C1516950
Children (2)
img Glomerular Basement Membrane C0599297
img Basilar Membrane C0004816
Ancestral Roots
RootRoot Plus OneDepthParent
img Tissues C0040300img Epithelium C00146093img Epithelium C0014609
img Normal Tissue Part C1519525img Epithelium Part C15169503img Epithelium Part C1516950
Relationships (156)

Relation Types:
anat_​to_​anat : 111
anat_​to_​chem : 31
anat_​to_​diso : 10
anat_​to_​phys : 4


Relationships:
none : 58
anatomic_​structure_​is_​physical_​part_​of : 2
gene_​product_​expressed_​in_​tissue : 1
gene_​product_​has_​associated_​anatomy : 7
has_​physical_​part_​of_​anatomic_​structure : 1
isa : 39
part_​of : 14
permuted_​term_​of : 1
sib_​in_​isa : 6
sib_​in_​part_​of : 27
Page Size
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Relation TypeCo-Occuring
Concept Count
RelationshipConcept
ANAT_to_PHYS47img physiological aspects C0031843
ANAT_to_CHEM45img Laminin C0022984
ANAT_to_DISO42img Retinal Perforations C0035321
ANAT_to_CHEM39img Laminin C0022984
ANAT_to_CHEM31img Collagen Type IV C0009333
ANAT_to_DISO31img Epiretinal Membrane C0339543
ANAT_to_CHEM29img Collagen Type IV C0009333
ANAT_to_CHEM26img Extracellular Matrix Protein C0079323
ANAT_to_CHEM26img Extracellular Matrix Proteins C0079323
ANAT_to_DISO25img Retinal Perforations C0035321
ANAT_to_PHYS22img Cell Movement C1621968
ANAT_to_ANAT21img Extracellular Matrix C0015350
ANAT_to_ANAT20img Extracellular Matrix C0015350
ANAT_to_ANAT20img Kidney Glomerulus C0022663
ANAT_to_ANAT20img Retina C0035298
ANAT_to_CHEM19img Indocyanine Green C0021234
ANAT_to_CHEM18img Coloring Agents C1566391
ANAT_to_ANAT17img Cell, Endothelial C0225336
ANAT_to_ANAT17img Epithelial Cells C0014597
ANAT_to_CHEM17img Coloring Agents C1566391
ANAT_to_ANAT16img Skin C1123023
ANAT_to_DISO15img Diabetic Retinopathy C0011884
ANAT_to_CHEM14img Abs - Autoantibodies C0004358
ANAT_to_CHEM14img Autoantibodies C0004358
ANAT_to_CHEM14img Collagen C0009325
Genes (6077)

Species:
human : 5377
mouse : 700
Page Size
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SpeciesGeneGeneIdGene NameEvidence
MouseTBC1D3B414059TBC1 domain family, member 3B
MouseNPNT255743nephronectin
MouseHIST1H2AA221613histone cluster 1, H2aa
MouseHIPK1204851homeodomain interacting protein kinase 1
MouseCADM4199731cell adhesion molecule 4
MousePAOX196743polyamine oxidase (exo-N4-amino)
MouseZNF384171017zinc finger protein 384
MouseASB8140461ankyrin repeat and SOCS box containing 8
MouseJDP2122953Jun dimerization protein 2
MouseHIST4H4121504histone cluster 4, H4
MouseSP7121340Sp7 transcription factor
MouseDCD117159dermcidin
MouseTNFRSF13C115650tumor necrosis factor receptor superfamily, member 13C
MouseSAT2112483spermidine/spermine N1-acetyltransferase family member 2
MouseEGLN2112398egl-9 family hypoxia-inducible factor 2
MouseHS6ST290161heparan sulfate 6-O-sulfotransferase 2
MousePSRC184722proline/serine-rich coiled-coil 1
MouseBEX284707brain expressed X-linked 2
MouseTBC1D3F84218TBC1 domain family, member 3F
MouseANTXR184168anthrax toxin receptor 1
MouseSOX783595SRY (sex determining region Y)-box 7
MouseZBP181030Z-DNA binding protein 1
MouseCD27680381CD276 molecule
MousePDCD1LG280380programmed cell death 1 ligand 2
MouseMUS8180198MUS81 structure-specific endonuclease subunit
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0004799Basement Membrane0self